INT303010

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Ptgis) endoplasmic reticulum (Ptgis) microtubule organizing center (Rock2)
cytoplasm (Rock2) extracellular space (Ptgis) nucleus (Rock2)
Ptgis (Rattus norvegicus)
Rock2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 12 55.12 Quite High
agonist 1 8.52 Low Low
Inflammation 5 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
sSRI 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 150 98.76 Very High Very High Very High
Hypoxia 7 98.28 Very High Very High Very High
Increased Venous Pressure Under Development 4 76.60 Quite High
Hypertrophy 36 63.60 Quite High
Pulmonary Heart Disease 1 62.20 Quite High
Disease 5 16.16 Low Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Natriuresis 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was reported that prostacyclin and its oral analogue beraprost may lack direct inhibitory effect on Rho-kinase in vitro, suggesting that combination therapy with a Rho-kinase inhibitor and beraprost is effective for the treatment of PAH.
prostacyclin Positive_regulation (effect) of Rho-kinase associated with pulmonary hypertension
1) Confidence 0.05 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 1.23 Pain Relevance 0.03

General Comments

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