INT303029

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.82
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TEK, Angpt1) extracellular region (TEK, Angpt1) plasma membrane (TEK, Angpt1)
cell differentiation (Angpt1) cell-cell signaling (TEK) cytoplasm (TEK)
TEK (Homo sapiens)
Angpt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 10 78.48 Quite High
cytokine 6 77.44 Quite High
chemokine 2 64.44 Quite High
antagonist 24 5.00 Very Low Very Low Very Low
Serotonin 10 5.00 Very Low Very Low Very Low
fluoxetine 6 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Hypertension 300 97.08 Very High Very High Very High
Apoptosis 8 94.92 High High
Adhesions 4 82.64 Quite High
INFLAMMATION 16 78.48 Quite High
Hypertrophy 72 75.08 Quite High
Stress 2 28.80 Quite Low
Hypoxia 14 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 8 5.00 Very Low Very Low Very Low
Natriuresis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cell-based gene transfer with angiopoietin-1 (Ang-1), a newly discovered ligand of the endothelial-specific tyrosine kinase receptor Tie-2, has been shown to improve survival and pulmonary hemodynamics in experimental PAH by a mechanism involving the inhibition of apoptosis and protection of the pulmonary microvasculature [58].

2.2.5.

Tie-2 Binding (ligand) of Ang-1 associated with pulmonary hypertension and apoptosis
1) Confidence 0.26 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.91 Pain Relevance 0.11
Cell-based gene transfer with angiopoietin-1 (Ang-1), a newly discovered ligand of the endothelial-specific tyrosine kinase receptor Tie-2, has been shown to improve survival and pulmonary hemodynamics in experimental PAH by a mechanism involving the inhibition of apoptosis and protection of the pulmonary microvasculature [58].

2.2.5.

Tie-2 Binding (ligand) of angiopoietin-1 associated with pulmonary hypertension and apoptosis
2) Confidence 0.26 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.91 Pain Relevance 0.11

General Comments

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