INT303170

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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Trim3, Shank1) cytoplasm (Trim3, Shank1) cell differentiation (Shank1)
plasma membrane (Shank1) protein complex assembly (Shank1)
Anatomy Link Frequency
head 2
Trim3 (Rattus norvegicus)
Shank1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 2 87.08 High High
tetrodotoxin 4 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 2 62.40 Quite High
Disease 1 55.24 Quite High
Intellectual Impairment 1 23.92 Low Low
Angelman Syndrome 1 21.12 Low Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Autism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of TRIM3 in hippocampal neurons suppresses GKAP protein levels, concomitant with loss of Shank1 and reduced spine head width.
Gene_expression (Overexpression) of TRIM3 in head Negative_regulation (suppresses) of GKAP protein
1) Confidence 0.40 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0.12 Pain Relevance 0.04

General Comments

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