INT303172

Context Info Confidence 0.22 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.13 Pain Relevance 0.13

intracellular (Trim3) plasma membrane (Dlgap1) cytoplasm (Trim3) cell-cell signaling (Dlgap1)

Dlgap1 (Rattus norvegicus) Trim3 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Glutamate receptor 4 92.56 tetrodotoxin 8 87.92 imagery 2 5.00

Disease Link Frequency Relevance Heat Syndrome 4 67.88 Disease 2 60.72 Intellectual Impairment 2 10.40 Angelman Syndrome 2 7.60 Anxiety Disorder 2 5.00 Attention Deficit Hyperactivity Disorder 2 5.00 Cognitive Disorder 2 5.00 Autism 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

TRIM3 is an E3 ligase for GKAP

GKAP Binding (ligase) of TRIM3

1) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0 Pain Relevance 0.09

In this study, we identify TRIM3 as a specific E3 ligase for GKAP.

GKAP Binding (ligase) of TRIM3

2) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0.13 Pain Relevance 0.05

General Comments

This test has worked.