INT303192

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Trim9) intracellular (Trim9) ligase activity (Trim9)
cytoplasm (Trim9)
Anatomy Link Frequency
finger 1
Trim9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 8 42.40 Quite Low
Glutamate receptor 4 37.00 Quite Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Angelman Syndrome 2 92.84 High High
Syndrome 4 91.84 High High
Intellectual Impairment 2 91.48 High High
Disease 2 5.16 Low Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Autism 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, TRIM9 overexpression robustly increased protein levels of HA-GKAP, HA-Shank1A and Myc-PSD-95 (Figure 3A, B), possibly by sequestering other components required for protein degradation.
Gene_expression (overexpression) of TRIM9
1) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0 Pain Relevance 0
In addition, we included two members of the TRIM/RBCC family of putative RING finger E3 ligases -- TRIM3 and TRIM9 -- that have been detected in the PSD by mass spectrometry [22].
Gene_expression (detected) of TRIM9 in finger
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0.28 Pain Relevance 0

General Comments

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