INT303195

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Shank1) plasma membrane (Shank1) intracellular (Shank1)
protein complex assembly (Shank1) cytoplasm (Shank1)
Anatomy Link Frequency
neurons 2
Shank1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 4 62.48 Quite High
Glutamate receptor 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 1 83.52 Quite High
Syndrome 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Intellectual Impairment 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Autism 1 5.00 Very Low Very Low Very Low
Angelman Syndrome 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In neurons expressing TRIM3/264 shRNA, bicuculline treatment failed to lower GKAP protein expression, despite a higher “baseline” level of GKAP (Figure 4D, E).
Neg (failed) Positive_regulation (lower) of Gene_expression (expression) of GKAP protein in neurons
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0.08 Pain Relevance 0.06

General Comments

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