INT303248

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LILRA3, Psd) signal transduction (LILRA3) extracellular region (LILRA3)
intracellular (Psd) cytoplasm (Psd)
Anatomy Link Frequency
neurons 2
LILRA3 (Homo sapiens)
Psd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate receptor 2 63.72 Quite High
tetrodotoxin 4 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Intellectual Impairment 1 68.40 Quite High
Syndrome 2 66.88 Quite High
Angelman Syndrome 1 65.60 Quite High
Disease 1 31.88 Quite Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Autism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To identify specific E3 ligases that mediate degradation of PSD proteins, we performed an RNAi screen of a subset of known and putative E3 enzymes in primary hippocampal neurons.
E3 Positive_regulation (mediate) of Protein_catabolism (degradation) of PSD in neurons
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0.20 Pain Relevance 0.03

General Comments

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