INT303365

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Myo1f)
Anatomy Link Frequency
head region 1
Myo1f (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 16.40 Low Low
imagery 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Sciatic nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscular Atrophy 9 98.28 Very High Very High Very High
Appetite Loss 1 97.52 Very High Very High Very High
Frailty 4 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Hypertrophy 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Nutritional Deficiencies 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evidence for ubiquitin-mediated degradation of myosin is mostly indirect, but the E3 ubiquitin ligases MuRF1, which is induced during muscle atrophy, and MuRF3 mediate the ubiquitination of soluble myosin in vitro [8], [9], binding to multiple sites near the head region of MyHC molecules.
Protein_catabolism (degradation) of myosin in head region associated with muscular atrophy
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0.29 Pain Relevance 0

General Comments

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