INT303410

Context Info Confidence 0.25 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.22 Pain Relevance 0.09

extracellular space (Ighg2b)

Anatomy Link Frequency B cell 1 Ighg2b (Mus musculus)

Pain Link Frequency Relevance Heat agonist 12 90.12 cytokine 7 5.00 isoflurane 6 5.00 anesthesia 2 5.00 Inflammation 2 5.00 Buprenorphine 2 5.00 ketamine 1 5.00 Pain management 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Immunization 103 98.86 Targeted Disruption 2 65.52 Influenza Virus Infection 73 53.88 Infection 12 25.76 Vesicular Stomatitis 2 7.88 Sprains And Strains 5 5.00 Increased Venous Pressure Under Development 4 5.00 Aging 3 5.00 Viral Infection 3 5.00 Toxicity 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our data do not exclude whether autonomous B cell expression of other PRRs, such as MDA5, is required for the IgG2c TI-2 antibody response.

Spec (whether) Regulation (response) of IgG2c in B cell

1) Confidence 0.25 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2901065 Disease Relevance 0.07 Pain Relevance 0.09

IgG subtype profiling (Fig. 5) showed that i.n. immunization with subunit vaccine alone induced low IgG1, IgG2a, and IgG2b responses.

Regulation (responses) of IgG2b associated with immunization

2) Confidence 0.13 Published 2010 Journal AAPS J Section Body Doc Link PMC2844513 Disease Relevance 1.15 Pain Relevance 0

General Comments

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