INT30345

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Context Info
Confidence 0.31
First Reported 1985
Last Reported 1986
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 2.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pomc, Penk) signal transduction (Pomc) generation of precursor metabolites and energy (Pomc)
extracellular space (Pomc) molecular_function (Pomc) cell-cell signaling (Pomc)
Anatomy Link Frequency
spinal 4
spinal cord 2
Pomc (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 22 100.00 Very High Very High Very High
analgesia 5 100.00 Very High Very High Very High
Morphine 5 100.00 Very High Very High Very High
Spinal cord 6 98.24 Very High Very High Very High
intrathecal 1 97.36 Very High Very High Very High
tail-flick 4 84.80 Quite High
narcan 1 62.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stereoselective effect of beta-endorphin on the production of analgesia and the spinal release of met-enkephalin in rats.
beta-endorphin Regulation (effect) of Localization (release) of met-enkephalin in spinal associated with enkephalin and analgesia
1) Confidence 0.31 Published 1986 Journal J. Pharmacol. Exp. Ther. Section Title Doc Link 3020229 Disease Relevance 0 Pain Relevance 1.07
Effect of beta-endorphin and morphine injected intraventricularly on the release of immunoreactive Met-enkephalin, Leu-enkephalin and dynorphin1-13 from the spinal cord was studied in anesthetized rats.
beta-endorphin Regulation (Effect) of Localization (release) of Met-enkephalin in spinal cord associated with enkephalin, spinal cord and morphine
2) Confidence 0.17 Published 1985 Journal Brain Res. Section Abstract Doc Link 2864105 Disease Relevance 0 Pain Relevance 1.00
The effect of intraventricular beta-endorphin-(1-27) on the spinal release of Met-enkephalin induced by intraventricular beta-endorphin was studied using the intrathecal superfusion technique in urethane anesthetized rats.
beta-endorphin Regulation (effect) of Localization (release) of Met-enkephalin in spinal associated with enkephalin and intrathecal
3) Confidence 0.14 Published 1986 Journal Int. J. Pept. Protein Res. Section Abstract Doc Link 2940195 Disease Relevance 0 Pain Relevance 0.54

General Comments

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