INT303531

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1f8) extracellular region (Il1f8) molecular_function (Il1f8)
biological_process (Il1f8)
Anatomy Link Frequency
keratinocytes 2
Il1f8 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 52 94.48 High High
cytokine 16 90.88 High High
Inflammatory response 10 80.16 Quite High
member 8 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 58 94.48 High High
Psoriasis 14 75.92 Quite High
Aging 8 75.08 Quite High
Dermatitis 12 56.64 Quite High
Acanthosis 16 54.68 Quite High
Alopecia 6 41.44 Quite Low
Targeted Disruption 28 5.00 Very Low Very Low Very Low
Congenital Anomalies 20 5.00 Very Low Very Low Very Low
Skin Diseases 10 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Concomitantly, expression of IL-1F8 was reduced by 30%, whereas no obvious change in the expression of claudin 1, claudin 3, or occludin was observed (unpublished data).
Negative_regulation (reduced) of Gene_expression (expression) of IL-1F8
1) Confidence 0.23 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.16 Pain Relevance 0.04
The first possibility seems unlikely because expression levels of S100A8/A9 and IL-1F8 were similar in cultured keratinocytes from mice of both genotypes.
Negative_regulation (levels) of Gene_expression (expression) of IL-1F8 in keratinocytes
2) Confidence 0.23 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.59 Pain Relevance 0.28

General Comments

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