INT303549

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1f6) extracellular region (Il1f6) cellular_component (Il1f6)
Anatomy Link Frequency
keratinocytes 2
Il1f6 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 26 98.86 Very High Very High Very High
cytokine 8 68.72 Quite High
Inflammatory mediators 1 66.68 Quite High
Inflammatory response 5 64.80 Quite High
psoriasis 1 39.68 Quite Low
member 8 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 14 99.88 Very High Very High Very High
Acanthosis 8 99.50 Very High Very High Very High
INFLAMMATION 29 98.86 Very High Very High Very High
Psoriasis 7 92.08 High High
Skin Diseases 5 78.00 Quite High
Injury 3 61.36 Quite High
Ichthyosis 1 52.80 Quite High
Stress 1 40.40 Quite Low
Hypertrophy 1 36.08 Quite Low
Dermatitis 6 20.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The role of IL-1F8 in the induction of the hyperproliferative phenotype is consistent with the cutaneous inflammation, hyperkeratosis, and acanthosis seen in transgenic mice overexpressing IL-1F6 in keratinocytes (Blumberg et al., 2007).
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of IL-1F6 in keratinocytes associated with targeted disruption, inflammation and acanthosis
1) Confidence 0.08 Published 2010 Journal The Journal of Cell Biology Section Body Doc Link PMC2845079 Disease Relevance 0.96 Pain Relevance 0.22

General Comments

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