INT303590

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 2
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.25
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (Ugcg) Golgi apparatus (Ugcg) lipid metabolic process (Ugcg)
Anatomy Link Frequency
lymphocytes 4
lung 2
Ugcg (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 16 94.00 High High
Inflammation 55 93.76 High High
Inflammatory response 24 81.44 Quite High
withdrawal 1 63.20 Quite High
corticosteroid 8 53.28 Quite High
metalloproteinase 1 31.24 Quite Low
cytokine 1 24.92 Low Low
chemokine 2 23.00 Low Low
agonist 1 18.80 Low Low
monoamine 26 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 205 100.00 Very High Very High Very High
Chronic Obstructive Pulmonary Disease 108 98.94 Very High Very High Very High
Lymphopenia 14 94.48 High High
Asthma 11 94.34 High High
Pulmonary Disease 1 94.04 High High
INFLAMMATION 82 93.76 High High
Apoptosis 12 81.28 Quite High
Disease 33 78.08 Quite High
Dyspnea 1 67.84 Quite High
Pneumonia 3 50.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, mice which derived from the vendor did not show increased GCs levels after acute stress exposure but still displayed a loss of lymphocytes from the circulation.
Negative_regulation (loss) of Neg (not) Positive_regulation (increased) of GCs in lymphocytes associated with stress
1) Confidence 0.19 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2845127 Disease Relevance 1.30 Pain Relevance 0.07
Interestingly, mice which derived from the vendor did not show increased GCs levels after acute stress exposure but still displayed a loss of lymphocytes from the circulation.
Negative_regulation (derived) of Neg (not) Positive_regulation (increased) of GCs in lymphocytes associated with stress
2) Confidence 0.19 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2845127 Disease Relevance 1.24 Pain Relevance 0.05
Although both inhaled and oral glucocorticoids (GCs) are effective at controlling inflammatory lung diseases such as asthma, their effectiveness is substantially less in COPD; therefore, their contribution to the management of stable COPD is limited.3,21 Results published from the TOwards a Revolution in COPD Health (TORCH) study of patients with COPD, with a FEV1 of <60%, indicated that regular use of inhaled GCs may decrease the rate of decline of lung function.22 However, the majority of studies have concluded that the use of regular inhaled GCs has no impact on the long-term progressive decline in FEV1.23–26
Spec (may) Negative_regulation (decrease) of Positive_regulation (inhaled) of GCs in lung associated with asthma, pulmonary disease, inflammation and chronic obstructive pulmonary disease
3) Confidence 0.04 Published 2010 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2939685 Disease Relevance 1.72 Pain Relevance 0.23

General Comments

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