INT303595

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) nucleus (Creb1) DNA binding (Creb1)
transcription factor binding (Creb1)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 90 90.08 High High
bDMF 20 88.88 High High
noradrenaline 4 85.52 High High
Serotonin 23 83.84 Quite High
fluoxetine 17 60.72 Quite High
sSRI 36 59.68 Quite High
nMDA receptor 15 55.80 Quite High
depression 56 52.72 Quite High
ketamine 2 45.40 Quite Low
nMDA receptor antagonist 5 41.12 Quite Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 38 96.88 Very High Very High Very High
Disease 97 76.84 Quite High
Death 5 68.56 Quite High
Depression 72 54.24 Quite High
Anxiety Disorder 1 47.16 Quite Low
Targeted Disruption 10 37.52 Quite Low
Neurodegenerative Disease 21 5.00 Very Low Very Low Very Low
Cognitive Disorder 20 5.00 Very Low Very Low Very Low
Dementia 11 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The authors speculate that inhibition of CREB translocation causes early synaptic dysfunction prior to the extracellular accumulation of amyloid peptide [136].
Negative_regulation (inhibition) of Localization (translocation) of CREB associated with alzheimer's dementia
1) Confidence 0.19 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2845130 Disease Relevance 0.86 Pain Relevance 0.57

General Comments

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