INT303596

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.21
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Atf6b) nucleus (Atf6b) intracellular (Atf6b)
DNA binding (Atf6b)
Atf6b (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 23 96.04 Very High Very High Very High
bDMF 20 87.92 High High
antidepressant 90 87.24 High High
fluoxetine 17 83.80 Quite High
sSRI 36 82.76 Quite High
nMDA receptor 15 78.88 Quite High
depression 56 75.80 Quite High
ketamine 2 68.48 Quite High
nMDA receptor antagonist 5 64.20 Quite High
agonist 2 50.76 Quite High
Disease Link Frequency Relevance Heat
Disease 97 99.96 Very High Very High Very High
Alzheimer's Dementia 38 98.86 Very High Very High Very High
Death 5 91.64 High High
Depression 72 77.32 Quite High
Anxiety Disorder 1 70.24 Quite High
Neurodegenerative Disease 21 13.36 Low Low
Frailty 1 12.16 Low Low
Stress 10 10.68 Low Low
Cognitive Disorder 20 5.00 Very Low Very Low Very Low
Dementia 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Amyloid peptide deposition, a major pathological feature of AD, interferes with the phosphorylation of cAMP-response element-binding protein (CREB) [135].
Negative_regulation (interferes) of Phosphorylation (phosphorylation) of cAMP-response element-binding protein associated with alzheimer's dementia and disease
1) Confidence 0.14 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2845130 Disease Relevance 1.21 Pain Relevance 0.82

General Comments

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