INT303690

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) extracellular space (KNG1) small molecule metabolic process (CPOX)
oxidoreductase activity (CPOX) extracellular region (KNG1) plasma membrane (KNG1)
Anatomy Link Frequency
epithelial cells 2
KNG1 (Homo sapiens)
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 82 100.00 Very High Very High Very High
Nicotine 192 81.28 Quite High
b2 receptor 58 63.04 Quite High
Inflammation 46 60.24 Quite High
agonist 22 50.00 Quite Low
antagonist 14 11.80 Low Low
dexamethasone 22 5.00 Very Low Very Low Very Low
B1 receptor 14 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 4 73.52 Quite High
Nicotine Addiction 24 71.36 Quite High
Asthma 30 65.00 Quite High
INFLAMMATION 46 60.24 Quite High
Hypersensitivity 4 59.72 Quite High
Pulmonary Disease 8 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 2 5.00 Very Low Very Low Very Low
Cough 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bradykinin and des-Arg9-bradykinin activate COX and stimulate the release of PGE2 from airway epithelial cells which induce airway relaxation through EP receptor activation [21].
bradykinin Positive_regulation (activate) of COX in epithelial cells associated with bradykinin
1) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2845563 Disease Relevance 0.38 Pain Relevance 0.48
Bradykinin and des-Arg9-bradykinin activate COX and stimulate the release of PGE2 from airway epithelial cells which induce airway relaxation through EP receptor activation [21].
Bradykinin Positive_regulation (activate) of COX in epithelial cells associated with bradykinin
2) Confidence 0.01 Published 2010 Journal Respir Res Section Body Doc Link PMC2845563 Disease Relevance 0.38 Pain Relevance 0.48

General Comments

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