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Context Info
Confidence 0.49
First Reported 1983
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 3.36
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (AMY2A) small molecule metabolic process (AMY2A) hydrolase activity, acting on glycosyl bonds (AMY2A)
extracellular region (AMY2A) carbohydrate metabolic process (AMY2A)
Anatomy Link Frequency
urine 1
AMY2A (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 78.80 Quite High
Codeine 1 74.40 Quite High
Inflammation 3 73.60 Quite High
cytokine 1 61.36 Quite High
Pain 7 50.00 Quite Low
Cholecystokinin 5 50.00 Quite Low
antagonist 3 50.00 Quite Low
Chronic pancreatitis 1 50.00 Quite Low
Lasting pain 1 50.00 Quite Low
Pain scale 1 50.00 Quite Low
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 2 99.52 Very High Very High Very High
Renal Failure 2 99.36 Very High Very High Very High
Renal Disease 10 97.44 Very High Very High Very High
Disorder Of Lipid Metabolism 7 80.84 Quite High
Cv General 3 Under Development 2 78.80 Quite High
Pressure And Volume Under Development 2 77.68 Quite High
Peptic Ulcer 2 76.76 Quite High
Pneumonia 2 75.88 Quite High
Cardiovascular Disease 2 75.24 Quite High
Disease 4 75.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the pain (+) group, the epidural block markedly decreased the VAS pain scale and salivary alpha-amylase from 56 +/- 22 to 19 +/- 16 mm (P < .01) and from 82 +/- 48 to 45 +/- 28 U/mL (P < .01), respectively, with a significant correlation between the 2 measures (r = 0.561, P < .01).
Negative_regulation (decreased) of alpha-amylase
1) Confidence 0.49 Published 2007 Journal Reg Anesth Pain Med Section Body Doc Link 17350522 Disease Relevance 0.07 Pain Relevance 0
RESULTS: The findings demonstrate that when receiving the reflexology treatment condition, as compared to the control condition, the residents demonstrated significant reduction in observed pain and salivary alpha-amylase.
Negative_regulation (reduction) of alpha-amylase
2) Confidence 0.41 Published 2008 Journal J Altern Complement Med Section Body Doc Link 18370580 Disease Relevance 0.06 Pain Relevance 0
Important decreases of alpha-amylase clearance in concordance with decreases of urea and creatinine clearances were observed in all the patients with severe renal failure.
Negative_regulation (decreases) of alpha-amylase associated with renal failure
3) Confidence 0.31 Published 1985 Journal Med Interne Section Abstract Doc Link 2864737 Disease Relevance 1.21 Pain Relevance 0.08
More moderate decreases of alpha-amylase clearance were observed in the patients with acute and chronic glomerulonephritis.
Negative_regulation (decreases) of alpha-amylase associated with renal disease
4) Confidence 0.31 Published 1985 Journal Med Interne Section Abstract Doc Link 2864737 Disease Relevance 1.21 Pain Relevance 0.07
The physical signs evaluated--abdominal tenderness and resistance--improved in all three loxiglumide groups, and the serum pancreatic amylase and trypsin levels decreased significantly in the 600-mg group (p < 0.05).
Negative_regulation (decreased) of serum pancreatic amylase
5) Confidence 0.12 Published 2002 Journal Pancreas Section Body Doc Link 12131781 Disease Relevance 0.05 Pain Relevance 0
[Test strips for the rapid determination of alpha-amylase in urine.
Negative_regulation (determination) of alpha-amylase in urine
6) Confidence 0.12 Published 1983 Journal Dtsch. Med. Wochenschr. Section Title Doc Link 6192986 Disease Relevance 0 Pain Relevance 0.07
These components also have the ability to inhibit certain enzymes like alpha amylase, glucosidase and lipase [11,14].
Negative_regulation (inhibit) of alpha amylase
7) Confidence 0.10 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2330043 Disease Relevance 0.75 Pain Relevance 0.13

General Comments

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