INT303706

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Bdkrb1) plasma membrane (Bdkrb1) signal transducer activity (Bdkrb1)
Bdkrb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nicotine 96 100.00 Very High Very High Very High
B1 receptor 41 100.00 Very High Very High Very High
b2 receptor 32 99.68 Very High Very High Very High
depression 46 83.88 Quite High
Neuropathic pain 1 77.20 Quite High
Central nervous system 7 74.76 Quite High
cytokine 35 67.80 Quite High
Inflammation 36 67.24 Quite High
Pain 2 59.28 Quite High
antagonist 32 57.36 Quite High
Disease Link Frequency Relevance Heat
Depression 55 83.88 Quite High
Neuropathic Pain 1 77.20 Quite High
Disease 5 76.36 Quite High
Epilepsy 1 75.52 Quite High
INFLAMMATION 38 67.24 Quite High
Pain 2 59.28 Quite High
Injury 3 46.64 Quite Low
Infection 5 46.32 Quite Low
Targeted Disruption 7 5.76 Low Low
Asthma 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of nicotine on airway kinin B1 and B2 receptor mRNA and protein expressions
Regulation (Effects) of Positive_regulation (airway) of kinin associated with nicotine and b2 receptor
1) Confidence 0.19 Published 2010 Journal Respir Res Section Body Doc Link PMC2845563 Disease Relevance 0 Pain Relevance 0.45
Efforts have also been made to define some of the mechanisms responsible for B1 receptor induction in the context of LPS-treated depressed animals by using biochemical and molecular techniques, such as flow cytometry, ELISA and real-time PCR.
Regulation (responsible) of Positive_regulation (induction) of B1 receptor associated with b1 receptor
2) Confidence 0.12 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3022820 Disease Relevance 0.64 Pain Relevance 0.40

General Comments

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