INT303840

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pon1) extracellular region (Pon1) lipid metabolic process (Pon1)
Pon1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 4 53.36 Quite High
Inflammation 1 41.44 Quite Low
Disease Link Frequency Relevance Heat
Stress 21 98.76 Very High Very High Very High
Pneumoperitoneum 11 83.52 Quite High
Disease 5 61.72 Quite High
Gallstones 3 61.40 Quite High
Hernia 3 55.12 Quite High
Diabetes Mellitus 2 44.56 Quite Low
Cancer 2 43.04 Quite Low
INFLAMMATION 1 41.44 Quite Low
Infection 1 39.04 Quite Low
Autoimmune Disease 1 37.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, roles for PON1 in a number of processes have been studied, including lipid and lipoprotein metabolism, as well as for their antiatherogenic and antioxidant properties.16–20 Oxidative stress, which is the result of an increased number of lipid and protein oxidation products and decreased number of antioxidant enzymes and vitamins, has been reported to affect the expression and activities of PON1.16, 20 Furthermore, oxidative stress has been shown to decrease PON1 activity and down-regulate the serum expression of PON1.16, 21–24
Regulation (affect) of Gene_expression (expression) of PON1 associated with stress
1) Confidence 0.22 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2845769 Disease Relevance 0.74 Pain Relevance 0.05

General Comments

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