INT303858

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.50
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DDR1, CXCR2) signal transduction (CXCR2) extracellular region (DDR1)
cell adhesion (DDR1) intracellular (CXCR2) signal transducer activity (CXCR2)
DDR1 (Homo sapiens)
CXCR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 85.72 High High
Inflammation 6 85.32 High High
Osteoarthritis 45 76.76 Quite High
metalloproteinase 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 28 99.00 Very High Very High Very High
Cancer 24 85.52 High High
INFLAMMATION 6 85.32 High High
Malignant Neoplastic Disease 3 84.00 Quite High
Osteoarthritis 45 76.76 Quite High
Osteophyte 5 70.16 Quite High
Hypertrophy 1 69.56 Quite High
Disease 12 52.44 Quite High
Arthritis 1 50.00 Quite Low
Ataxia 1 35.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, IL-8/CXCR2 tandem is transcriptionally induced by the DDR and participates to the senescence-dependent cell cycle arrest by producing more ROS [39].
DDR Positive_regulation (induced) of CXCR2 associated with aging
1) Confidence 0.11 Published 2010 Journal The Open Rheumatology Journal Section Body Doc Link PMC2845788 Disease Relevance 1.50 Pain Relevance 0.42

General Comments

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