INT303901

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd5)
Anatomy Link Frequency
B-cells 2
Cd5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 11 81.04 Quite High
cytokine 1 59.12 Quite High
methotrexate 2 36.28 Quite Low
corticosteroid 3 32.32 Quite Low
Demyelination 2 13.76 Low Low
Neuritis 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 98.28 Very High Very High Very High
Necrosis 1 94.88 High High
Cancer 1 94.52 High High
INFLAMMATION 11 81.04 Quite High
Multiple Sclerosis 1 74.72 Quite High
Uveitis 1 70.16 Quite High
Disease 4 69.88 Quite High
Idiopathic Thrombocytopenic Purpura 1 65.52 Quite High
Chronic Inflammatory Demyelinating Polyradiculoneuropathy 33 52.24 Quite High
Demyelinating Disease 9 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
,34 induction of B-cell apoptosis,35 downregulation of specific auto-reactive B-cells and regulation of B-cell subsets expressing CD5,36 thereby suppressing the auto-antibody producing CD20+ B1 cells.
Negative_regulation (suppressing) of in B-cells Gene_expression (expressing) of CD5 in B-cell associated with apoptosis
1) Confidence 0.19 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2846143 Disease Relevance 0.88 Pain Relevance 0.13

General Comments

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