INT303966

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.41
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lep) extracellular space (Lep) extracellular region (Lep)
intracellular (Lep) lipid metabolic process (Lep)
Anatomy Link Frequency
NK cells 1
Lep (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 5 69.76 Quite High
cytokine 40 68.44 Quite High
Inflammation 27 68.04 Quite High
Osteoarthritis 108 50.00 Quite Low
Pain 25 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
Neurobehavioral 7 5.00 Very Low Very Low Very Low
tail-flick 6 5.00 Very Low Very Low Very Low
Eae 5 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 98 85.28 High High
Frailty 1 76.00 Quite High
INFLAMMATION 33 68.04 Quite High
Adhesions 2 61.20 Quite High
Diabetes Mellitus 2 53.36 Quite High
Osteoarthritis 87 50.00 Quite Low
Knee Osteoarthritis 34 25.36 Quite Low
Endotoxemia 1 23.68 Low Low
Uremia 1 21.40 Low Low
Apoptosis 6 18.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Leptin had no affect on IL-1?
Leptin Neg (no) Regulation (affect) of IL-1
1) Confidence 0.09 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945020 Disease Relevance 0 Pain Relevance 0
Besides, leptin mediates the activation of NK cells indirectly by modulation of IL-1?
leptin Regulation (modulation) of IL-1 in NK cells
2) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.41 Pain Relevance 0.10

General Comments

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