INT303988

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (ISYNA1) signal transduction (Lep) extracellular space (Lep)
extracellular region (Lep) intracellular (Lep) cytoplasm (ISYNA1)
Lep (Mus musculus)
ISYNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 24 91.28 High High
spinal inflammation 1 87.44 High High
Inflammation 9 68.28 Quite High
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 2 93.36 High High
Low Back Pain 1 87.44 High High
Osteoarthritis 1 71.84 Quite High
INFLAMMATION 12 68.28 Quite High
Obesity 22 56.96 Quite High
Stress 3 56.24 Quite High
Apoptosis 6 55.04 Quite High
Body Weight 1 6.72 Low Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, leptin alone or in combination with IL-1 enhanced the expression of iNOS and COX-2 and production of NO, PGE (2), IL-6, and IL-8.
leptin Positive_regulation (enhanced) of Gene_expression (expression) of iNOS
1) Confidence 0.06 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.55 Pain Relevance 0.23

General Comments

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