INT303989

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep, IL12A) extracellular region (Lep, IL12A) signal transduction (Lep)
intracellular (Lep) cytoplasm (IL12A) lipid metabolic process (Lep)
Anatomy Link Frequency
NK cells 1
Lep (Mus musculus)
IL12A (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 3 75.48 Quite High
cytokine 24 74.16 Quite High
Inflammation 9 73.76 Quite High
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 22 75.04 Quite High
INFLAMMATION 12 73.76 Quite High
Adhesions 2 66.92 Quite High
Frailty 1 65.76 Quite High
Diabetes Mellitus 1 59.08 Quite High
Uremia 1 27.12 Quite Low
Endotoxemia 1 13.44 Low Low
Apoptosis 6 8.48 Low Low
Stress 3 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Leptin enhances both the development and the activation of NK cells [50], increasing IL-12 and reducing the expression of IL-15 [51].
Leptin Positive_regulation (increasing) of IL-12 in NK cells
1) Confidence 0.05 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.39 Pain Relevance 0.11

General Comments

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