INT303993

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep, IL2) extracellular region (Lep, IL2) signal transduction (Lep)
cell adhesion (IL2) intracellular (Lep) cell-cell signaling (IL2)
Anatomy Link Frequency
NK cells 2
Lep (Mus musculus)
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 48 97.04 Very High Very High Very High
chemokine 6 88.44 High High
Inflammation 18 86.72 High High
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
endometriosis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 86.72 High High
Adhesions 4 79.88 Quite High
Diabetes Mellitus 2 72.04 Quite High
Obesity 44 45.92 Quite Low
Uremia 2 40.08 Quite Low
Frailty 2 36.64 Quite Low
Apoptosis 12 19.28 Low Low
Stress 6 5.00 Very Low Very Low Very Low
Autoimmune Disease 6 5.00 Very Low Very Low Very Low
Metabolic Syndrome 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, human leptin enhances the production of IL-2 and IFN-?
leptin Positive_regulation (enhances) of Gene_expression (production) of IL-2
1) Confidence 0.15 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0 Pain Relevance 0.17
Moreover, leptin increases IL-2 and perforin gene expression at the transcription levels in NK cells.
leptin Positive_regulation (increases) of Gene_expression (expression) of IL-2 in NK cells
2) Confidence 0.10 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.24 Pain Relevance 0.16

General Comments

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