INT303995

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PSME1) small molecule metabolic process (PSME1) intracellular (Lep)
cytoplasm (PSME1) lipid metabolic process (Lep) cytosol (PSME1)
Anatomy Link Frequency
monocytes 1
Lep (Mus musculus)
PSME1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 100.00 Very High Very High Very High
chemokine 3 92.16 High High
cytokine 24 89.40 High High
Inflammation 9 69.08 Quite High
Inflammatory stimuli 2 54.88 Quite High
withdrawal 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 69.08 Quite High
Infection 2 65.24 Quite High
Apoptosis 6 60.48 Quite High
Obesity 22 49.80 Quite Low
Congenital Anomalies 2 48.04 Quite Low
Stress 3 23.36 Low Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low
Atherosclerosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Later, it was found that leptin directly induces the secretion of interleukin 1 receptor antagonist in human monocytes [26] and upregulates IP-10 (interferon-gamma-inducible protein) in monocytic cells [27].
leptin Positive_regulation (upregulates) of interferon-gamma-inducible protein in monocytes associated with antagonist
1) Confidence 0.09 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.32 Pain Relevance 0.29

General Comments

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