INT303997

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL1RL1, Lep) extracellular space (IL1RL1, Lep) extracellular region (IL1RL1, Lep)
intracellular (IL1RL1, Lep) plasma membrane (IL1RL1) lipid metabolic process (Lep)
Anatomy Link Frequency
T lymphocytes 1
IL1RL1 (Homo sapiens)
Lep (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 24 70.28 Quite High
endometriosis 1 64.04 Quite High
Inflammation 9 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 89.52 High High
Endometriosis (extended) 1 64.04 Quite High
Pressure And Volume Under Development 1 51.32 Quite High
Obesity 22 40.44 Quite Low
Apoptosis 6 34.60 Quite Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low
Atherosclerosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human leptin alone is not able to activate human peripheral blood lymphocytes in vitro [23] even though leptin receptor is present and activated in T lymphocytes upon leptin stimulation, fully triggering the intracellular signal transduction, as we have also assessed [60, 61].
stimulation Neg (not) Positive_regulation (activated) of leptin in T lymphocytes
1) Confidence 0.01 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.20 Pain Relevance 0.07

General Comments

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