INT304025

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PIK3CA, TP53) cell differentiation (TP53) nucleoplasm (TP53)
mitochondrion (TP53) endoplasmic reticulum (TP53) enzyme binding (TP53)
PIK3CA (Homo sapiens)
TP53 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 18 97.80 Very High Very High Very High
Adenocarcinoma 6 75.04 Quite High
Endometrial Cancer 153 72.68 Quite High
Endometroid Carcinoma 21 72.24 Quite High
Cancer 85 55.84 Quite High
Apoptosis 16 55.76 Quite High
Carcinoma 61 50.08 Quite High
Microsatellite Instability 47 5.00 Very Low Very Low Very Low
Endometrial Stromal Sarcoma 39 5.00 Very Low Very Low Very Low
Carcinosarcoma 29 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, interactions between the PI3K/AKT and p53 signaling pathways have been described in which activation of the PI3K/AKT pathway through PTEN or PIK3CA mutations, together with p53 inactivation, results in malignant transformation [15].
PIK3CA Binding (interactions) of p53 associated with malignant neoplastic disease
1) Confidence 0.30 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 0.67 Pain Relevance 0

General Comments

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