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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FOXA2) DNA binding (FOXA2) transcription factor binding (FOXA2)
cytoplasm (FOXA2)
FOXA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Cancer 153 99.32 Very High Very High Very High
Apoptosis 16 76.20 Quite High
Congenital Anomalies 2 69.24 Quite High
Aneuploidy 3 64.00 Quite High
Malignant Neoplastic Disease 18 62.72 Quite High
Adenocarcinoma 6 43.16 Quite Low
Endometrial Hyperplasia 4 42.44 Quite Low
Microsatellite Instability 47 40.32 Quite Low
Necrosis 1 29.52 Quite Low
Cancer 85 29.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intestinal trefoil protein, TFF3, AGR2 developmental gene, estrogen-regulated genes (MGB2, LTF, END1, MMP11), FOXA2, and MSX2 were significantly up-regulated in endometrioid endometrial carcinomas, while increased expression of FOLR, genes involved in the regulation of mitotic spindle checkpoint (STK15, BUB1, CCNB2), IGF2, PTGS1 and p16 were seen in non-endometrioid endometrial carcinomas.
Positive_regulation (regulated) of FOXA2 associated with endometrial cancer
1) Confidence 0.15 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.29 Pain Relevance 0

General Comments

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