INT304079

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (AGR2) extracellular region (AGR2) endoplasmic reticulum (AGR2)
AGR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 5 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Cancer 153 97.04 Very High Very High Very High
Apoptosis 16 79.24 Quite High
Congenital Anomalies 2 72.28 Quite High
Aneuploidy 3 57.60 Quite High
Malignant Neoplastic Disease 28 56.32 Quite High
Pancreatic Cancer 47 49.68 Quite Low
Adenocarcinoma 9 46.20 Quite Low
Endometrial Hyperplasia 4 45.48 Quite Low
Microsatellite Instability 47 33.92 Quite Low
Necrosis 1 32.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To assess the effects of serum on the AGR2 ELISA, we added 10% Normal Human Serum (NHS) to a subset of samples.
Regulation (effects) of AGR2
1) Confidence 0.27 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2893103 Disease Relevance 0 Pain Relevance 0
Intestinal trefoil protein, TFF3, AGR2 developmental gene, estrogen-regulated genes (MGB2, LTF, END1, MMP11), FOXA2, and MSX2 were significantly up-regulated in endometrioid endometrial carcinomas, while increased expression of FOLR, genes involved in the regulation of mitotic spindle checkpoint (STK15, BUB1, CCNB2), IGF2, PTGS1 and p16 were seen in non-endometrioid endometrial carcinomas.
Regulation (regulated) of AGR2 associated with endometrial cancer
2) Confidence 0.11 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.20 Pain Relevance 0

General Comments

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