INT304098

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 5.78
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il13) extracellular region (Il13) cytoplasm (Il13)
Anatomy Link Frequency
blood 1
Il13 (Mus musculus)
Aia1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 5 98.60 Very High Very High Very High
Inflammation 70 94.96 High High
aspirin 40 75.00 Quite High
cINOD 10 49.36 Quite Low
cytokine 10 15.08 Low Low
Disease Link Frequency Relevance Heat
Asthma 410 100.00 Very High Very High Very High
Rhinitis 95 100.00 Very High Very High Very High
INFLAMMATION 75 94.96 High High
Chronic Sinusitis 20 83.72 Quite High
Eczema 5 82.24 Quite High
Hypersensitivity 20 78.72 Quite High
Eosinophilia 15 59.56 Quite High
Urticaria 5 53.28 Quite High
Nasal Polyps 10 52.48 Quite High
Adhesions 5 37.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other AIA-related phenotypes, such as the total serum IgE level and log PC20 methacholine, were not associated with the three polymorphisms of the IL-13 gene.


IL-13 Binding (associated) of AIA associated with asthma
1) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846737 Disease Relevance 1.02 Pain Relevance 0.03
Therefore, we also investigated the number of blood eosinophils in the patients with AIA associated with the IL-13 polymorphisms.
IL-13 Binding (associated) of AIA in blood associated with asthma
2) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846737 Disease Relevance 1.33 Pain Relevance 0.15
Although IL-13 is associated with asthma and atopy, no studies have evaluated its association with AIA.
IL-13 Binding (association) of AIA associated with asthma and rhinitis
3) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846737 Disease Relevance 1.36 Pain Relevance 0.10
1-509C>T polymorphism was reported to have a significant association with the frequency of rhinosinusitis in AIA patients.25 Furthermore, our data on the gene-gene interaction between IL-10 and TGFb1 suggest its association with the development of AIA with rhinosinusitis.26 In this study, we found a significantly higher frequency of rhinosinusitis in AIA associated with the three IL-13 polymorphisms.
IL-13 Binding (associated) of AIA associated with asthma
4) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846737 Disease Relevance 1.10 Pain Relevance 0
These findings suggest that the IL-13 polymorphisms at -1510A>C and 1055C>T are associated with the development of rhinosinusitis in AIA patients.
IL-13 Binding (associated) of AIA associated with asthma
5) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Abstract Doc Link PMC2846737 Disease Relevance 0.97 Pain Relevance 0.14

General Comments

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