INT304170

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Apaf1, Casp9) nucleus (Apaf1, Casp9) cytoplasm (Apaf1, Casp9)
peptidase activity (Casp9) mitochondrion (Casp9) Golgi apparatus (Apaf1)
Apaf1 (Mus musculus)
Casp9 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 24 5.00 Very Low Very Low Very Low
Inflammation 17 5.00 Very Low Very Low Very Low
corticosteroid 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
lidocaine 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 77 96.18 Very High Very High Very High
Death 22 42.56 Quite Low
Eosinophilia 16 24.36 Low Low
Asthma 24 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Hypereosinophilic Syndrome 17 5.00 Very Low Very Low Very Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Hypersensitivity 15 5.00 Very Low Very Low Very Low
Rhinitis 11 5.00 Very Low Very Low Very Low
Eczema 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, caspase-8 can be activated following recruitment and clustering at multicomponent apoptosis-signaling complexes, resulting from ligation of cell surface molecules of the TNF receptor family, presumably by auto-processing of the zymogens according to the induced-proximity model.116 Caspase-9 is activated by recruitment to Apaf-1 in the presence of ATP following release of cytochrome c from mitochondria.117
Apaf-1 Binding (recruitment) of Positive_regulation (activated) of Caspase-9 associated with apoptosis
1) Confidence 0.01 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846745 Disease Relevance 0.51 Pain Relevance 0

General Comments

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