INT304182

Context Info Confidence 0.12 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.59 Pain Relevance 0

ribosome (Rps6ka1) nucleus (Rps6ka1) kinase activity (Rps6ka1) transcription factor binding (Rps6ka1) cytoplasm (Rps6ka1)

Rps6ka1 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 7 18.24 anesthesia 1 5.00 isoflurane 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 15 92.88 Cancer 84 57.96 Pressure And Volume Under Development 1 56.84 Malignant Neoplastic Disease 3 56.52 Metastasis 1 56.08 Disease 2 53.48 Pancreatic Cancer 21 50.00 Death 3 47.84 Adenocarcinoma 11 46.20 Hypertension 1 10.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These effects are executed through a heterotrimeric G protein-coupled receptor, which mediates Ang II transactivated epidermal growth factor (EGF)-induced activation of MEK (MAPK kinase 1) and ERK [12].

Positive_regulation (induced) of Positive_regulation (activation) of MAPK kinase 1

1) Confidence 0.12 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2846883 Disease Relevance 0.59 Pain Relevance 0

General Comments

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