INT304279

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.83
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ETS1, MMP2) DNA binding (ETS1) peptidase activity (MMP2)
extracellular space (MMP2) extracellular region (MMP2) cell motility (ETS1)
ETS1 (Homo sapiens)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 73.28 Quite High
Chronic pancreatitis 25 71.92 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 96 99.24 Very High Very High Very High
Apoptosis 27 93.56 High High
Disease 16 91.48 High High
Pancreatic Cancer 28 78.48 Quite High
Carcinoma 29 76.08 Quite High
INFLAMMATION 28 73.28 Quite High
Pancreatitis 26 71.92 Quite High
Cancer 82 51.36 Quite High
Hepatocellular Cancer 1 47.92 Quite Low
Solid Tumor 4 37.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results points to that the COX-2 product PGE2 mediated PDAC cellular invasiveness through an ERK/Ets-1-dependent induction of MMP-2 expression and activity [36].
Ets-1 Positive_regulation (induction) of MMP-2 associated with adenocarcinoma
1) Confidence 0.05 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2847547 Disease Relevance 1.83 Pain Relevance 0.17

General Comments

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