INT304281

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.35
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TBK1) signal transduction (IL8) extracellular space (IL8)
extracellular region (IL8) plasma membrane (TBK1) intracellular (IL8)
IL8 (Homo sapiens)
TBK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 100.00 Very High Very High Very High
Chronic pancreatitis 25 99.62 Very High Very High Very High
fibrosis 1 59.52 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 100.00 Very High Very High Very High
Adenocarcinoma 96 99.80 Very High Very High Very High
Pancreatitis 26 99.62 Very High Very High Very High
Metastasis 6 97.08 Very High Very High Very High
Hepatocellular Cancer 1 87.64 High High
Cancer 82 85.24 High High
Pancreatic Cancer 28 81.20 Quite High
Carcinoma 29 80.72 Quite High
Disease 16 70.72 Quite High
Fibrosis 2 59.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar inflammatory components and downstream effectors have been found to be elevated in CP and PDAC, such as CXCL8, an activator of inflammatory NF-kB cascade and associated with tumorigenesis by promoting angiogenesis and metastasis [37].
CXCL8 Positive_regulation (activator) of NF-kB associated with adenocarcinoma, inflammation, chronic pancreatitis and metastasis
1) Confidence 0.01 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2847547 Disease Relevance 2.35 Pain Relevance 0.44

General Comments

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