INT304321

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.59
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA) signal transducer activity (Ptger4) signal transduction (Ptger4)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
Anatomy Link Frequency
cochlea 2
inner ear 2
Ptger4 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 108 98.80 Very High Very High Very High
Central nervous system 4 85.20 High High
anesthesia 6 5.00 Very Low Very Low Very Low
Versed 6 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 4 97.28 Very High Very High Very High
Ganglion Cysts 34 89.84 High High
Injury 14 86.80 High High
Sensorineural Hearing Loss 20 67.20 Quite High
Fibromyalgia 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings provide new insights into the mechanisms underlying the regulation of VEGF expression in the cochlea, which is mediated by EP2 and EP4.
EP4 Positive_regulation (mediated) of Gene_expression (expression) of VEGF in cochlea
1) Confidence 0.27 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2847564 Disease Relevance 0.36 Pain Relevance 0.04
ELISA and real-time qRT-PCR analyses demonstrated an increase of VEGF protein and mRNA levels in the inner ear after local EP2 or EP4 agonist application, indicating that the stimulation of EP2 and/or EP4 activates VEGF production in the inner ear.
EP4 Positive_regulation (activates) of Gene_expression (production) of VEGF in inner ear associated with agonist
2) Confidence 0.25 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2847564 Disease Relevance 0.23 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox