INT304441

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2rx4) transport (P2rx4) plasma membrane (P2rx4)
Anatomy Link Frequency
C8-B4 2
P2rx4 (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 35 97.70 Very High Very High Very High
Endep 16 66.72 Quite High
fluoxetine 3 60.20 Quite High
Desipramine 3 59.72 Quite High
antagonist 6 50.24 Quite High
Neuropathic pain 9 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 11 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Why do pre-applications of antidepressants lead to a reduction in P2X4 receptor responses in activated C8-B4 cells (Fig. 12), even though these drugs do not inhibit P2X4 receptors directly (Fig. 11)?
Negative_regulation (inhibit) of P2X4 Binding (receptors) of in C8-B4 associated with antidepressant
1) Confidence 0.37 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.49

General Comments

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