INT304457

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx4) mitochondrion (Ass1) endoplasmic reticulum (Ass1)
ligase activity (Ass1) cytoplasm (Ass1) signal transduction (P2rx4)
Anatomy Link Frequency
C8-B4 2
Ass1 (Mus musculus)
P2rx4 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 1 54.44 Quite High
gABA 1 53.64 Quite High
imagery 6 43.24 Quite Low
antidepressant 35 5.00 Very Low Very Low Very Low
Endep 16 5.00 Very Low Very Low Very Low
Neuropathic pain 9 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
Desipramine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 12.64 Low Low
Neuropathic Pain 11 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, of these, only P2X4 transcript levels were significantly increased by 2.4-fold in C8-B4 cells activated (Fig. 3) using conditions that give rise to ATP-evoked inward currents (Fig. 2).


2.4-fold Positive_regulation (increased) of Transcription (levels) of P2X4 in C8-B4
1) Confidence 0.01 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.05

General Comments

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