INT304499

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Map2k1, Mapk1) nucleus (Map2k1, Mapk1) Golgi apparatus (Map2k1, Mapk1)
cytoplasm (Map2k1, Mapk1) cytosol (Map2k1, Mapk1) cytoskeleton (Map2k1, Mapk1)
Map2k1 (Rattus norvegicus)
Mapk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 55 83.68 Quite High
medulla 11 5.00 Very Low Very Low Very Low
Cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 62 90.08 High High
Apoptosis 2 90.08 High High
Poisoning 7 65.84 Quite High
Toxicity 2 34.88 Quite Low
Pressure Volume 2 Under Development 4 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Critical Illness 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As a member of the mitogen-activated protein kinases (MAPKs), ERK1/2 pathway is activated specifically by MAPK kinase 1/2 (MEK1/2), and is an important signal for cell survival [14-19].
MEK1 Positive_regulation (activated) of ERK1/2
1) Confidence 0.12 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.80 Pain Relevance 0.10

General Comments

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