INT304503

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Map2k1, Nos1) cytoplasm (Map2k1, Nos1) cytosol (Map2k1, Nos1)
nucleus (Map2k1, Nos1) cytoskeleton (Map2k1, Nos1) plasma membrane (Map2k1, Nos1)
Anatomy Link Frequency
brain stem 1
Map2k1 (Rattus norvegicus)
Nos1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 55 100.00 Very High Very High Very High
anesthesia 1 6.32 Low Low
medulla 11 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 62 100.00 Very High Very High Very High
Poisoning 7 98.80 Very High Very High Very High
Apoptosis 2 85.36 High High
Toxicity 2 12.32 Low Low
Pressure Volume 2 Under Development 4 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Critical Illness 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on our Mev intoxication model [4], the present study evaluated the hypothesis that MEK1/2 and ERK1/2 in RVLM play a pro-life role during brain stem death by activating the NOS I/PKG cascade.
MEK1 Positive_regulation (activating) of NOS I in brain stem associated with rostral ventrolateral medulla, death and poisoning
1) Confidence 0.07 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.66 Pain Relevance 0.16

General Comments

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