INT304512

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mknk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 11 86.48 High High
Rostral ventrolateral medulla 55 71.28 Quite High
cerebral cortex 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Poisoning 7 57.52 Quite High
Death 62 55.32 Quite High
Overdose 1 15.44 Low Low
Peripheral Arterial Disease 1 14.36 Low Low
Pressure Volume 2 Under Development 4 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Critical Illness 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Test agents used included Mev (kindly provided by Huikwang Corporation, Tainan, Taiwan), a specific ERK2 inhibitor [25], ERK activation inhibitor peptide II (Calbiochem, San Diego, CA, USA); a specific MEK1/2 inhibitor [26,27], U0126 (Calbiochem); or a specific MNK1/2 inhibitor [28,29], CGP57380 (Tocris, Ellisville, MO, USA).
Negative_regulation (inhibitor) of MNK1
1) Confidence 0.33 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.17 Pain Relevance 0.08

General Comments

This test has worked.

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