INT304536

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PRKG1) signal transduction (PRKG1) plasma membrane (PRKG1)
cytoplasm (PRKG1)
Mknk1 (Rattus norvegicus)
PRKG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 55 93.24 High High
Inflammatory response 1 82.64 Quite High
medulla 11 80.72 Quite High
cerebral cortex 1 68.00 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 62 96.88 Very High Very High Very High
INFLAMMATION 1 82.64 Quite High
Middle Cerebral Artery Infarction 1 75.12 Quite High
Apoptosis 2 46.40 Quite Low
Poisoning 7 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 4 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low
Critical Illness 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We further showed that mechanistically, this pro-life role was executed via upregulation of the pro-life NOS I/PKG signaling cascade by MNK1/2.
MNK1 Positive_regulation (upregulation) of PKG
1) Confidence 0.03 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2848001 Disease Relevance 0.53 Pain Relevance 0.30

General Comments

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