INT304577

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Arntl, Clock) cytoplasm (Arntl, Clock) signal transducer activity (Arntl, Clock)
signal transduction (Arntl, Clock) nucleus (Arntl, Clock) transcription factor binding (Arntl, Clock)
Arntl (Mus musculus)
Clock (Mus musculus)
Maoa (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 16 100.00 Very High Very High Very High
Dopamine 9 91.56 High High
Neurotransmitter 3 86.92 High High
depression 73 64.08 Quite High
Ventral tegmentum 4 56.40 Quite High
antidepressant 42 36.72 Quite Low
agonist 1 31.84 Quite Low
bDMF 26 5.00 Very Low Very Low Very Low
Hippocampus 15 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 81 64.08 Quite High
Manic Depressive Disorder 6 63.72 Quite High
Affective Disorder 19 45.12 Quite Low
Seasonal Affective Disorder 1 37.00 Quite Low
Neurodegenerative Disease 19 5.92 Low Low
Stress 17 5.00 Very Low Very Low Very Low
Congenital Anomalies 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Shock 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, monoamine oxidase-A (MAO-A) expression is regulated by dimer formation of Clock and Bmal1, and MAO-A activity accordingly shows a circadian rhythmicity [118].
Bmal1 Binding (formation) of Clock Regulation (regulated) of Gene_expression (expression) of monoamine oxidase associated with monoamine
1) Confidence 0.01 Published 2010 Journal Mol Brain Section Body Doc Link PMC2848031 Disease Relevance 0.30 Pain Relevance 0.44

General Comments

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