INT304578

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf) nucleus (HDAC9)
transcription factor binding (HDAC9) cytoplasm (HDAC9)
Anatomy Link Frequency
brain 3
HDAC9 (Homo sapiens)
Bdnf (Mus musculus)
Pain Link Frequency Relevance Heat
bDMF 26 100.00 Very High Very High Very High
depression 73 86.56 High High
imagery 5 77.52 Quite High
antidepressant 42 71.80 Quite High
Hippocampus 15 70.68 Quite High
monoamine 16 5.00 Very Low Very Low Very Low
Dopamine 9 5.00 Very Low Very Low Very Low
withdrawal 8 5.00 Very Low Very Low Very Low
amygdala 5 5.00 Very Low Very Low Very Low
Ventral tegmentum 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 81 86.56 High High
Affective Disorder 19 81.84 Quite High
Neurodegenerative Disease 19 79.04 Quite High
Stress 17 59.52 Quite High
Repression 2 56.28 Quite High
Shock 3 32.12 Quite Low
Manic Depressive Disorder 6 5.00 Very Low Very Low Very Low
Congenital Anomalies 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another study showed that HDAC inhibitors such as VPA, SB, and TSA increase BDNF expression in the brain [51].
Negative_regulation (inhibitors) of HDAC in brain Positive_regulation (increase) of Gene_expression (expression) of BDNF in brain associated with bdmf
1) Confidence 0.06 Published 2010 Journal Mol Brain Section Body Doc Link PMC2848031 Disease Relevance 0.90 Pain Relevance 0.49

General Comments

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