INT304887

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Agtr2, Mapk1) transcription factor binding (Agtr2, Mapk1) nucleoplasm (Mapk1)
mitochondrion (Mapk1) protein complex (Mapk1) cytoplasm (Mapk1)
Anatomy Link Frequency
fibroblasts 2
Agtr2 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 68.32 Quite High
tetrodotoxin 1 60.04 Quite High
Inflammation 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 1 99.00 Very High Very High Very High
Diabetes Mellitus 127 96.96 Very High Very High Very High
Stress 19 55.04 Quite High
Neurodegenerative Disease 8 50.00 Quite Low
Body Weight 6 42.52 Quite Low
Apoptosis 8 30.28 Quite Low
Diabetic Retinopathy 8 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 5 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In cardiac fibroblasts, angiotensin II increases the intracellular ROS and ERK activation through AT1R, to induce cardiac hypertrophy.
angiotensin II Positive_regulation (increases) of Positive_regulation (activation) of ERK in fibroblasts associated with coronary heart disease
1) Confidence 0.10 Published 2010 Journal Diabetologia Section Body Doc Link PMC2850533 Disease Relevance 0.45 Pain Relevance 0.09

General Comments

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