INT305011

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 4.02
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (NREP) cytoplasm (NREP)
NREP (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 1 87.44 High High
Inflammation 6 77.84 Quite High
cytokine 5 63.76 Quite High
metalloproteinase 3 46.00 Quite Low
Pain 5 5.00 Very Low Very Low Very Low
pruritus 4 5.00 Very Low Very Low Very Low
dysesthesia 4 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Keloid Scars 226 99.84 Very High Very High Very High
Cicatrix 56 97.64 Very High Very High Very High
Burns 16 96.20 Very High Very High Very High
Injury 31 92.56 High High
Dermal Scarring 48 92.44 High High
Disease 29 87.88 High High
Osteoarthritis 1 87.44 High High
INFLAMMATION 6 77.84 Quite High
Wound Healing 15 76.36 Quite High
Contracture 4 75.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, C5ORF13, also known as P311, has also been implicated to be a negative regulator for TGF-?
Positive_regulation (implicated) of C5ORF13
1) Confidence 0.44 Published 2010 Journal Eplasty Section Body Doc Link PMC2851107 Disease Relevance 0.76 Pain Relevance 0.04
Among these P311 gene expression increased conspicuously in hypertrophic scar tissue [3].
Positive_regulation (increased) of P311 associated with keloid scars
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852399 Disease Relevance 1.11 Pain Relevance 0.07
However, the upregulation of P311 did increased the expression of ?
Positive_regulation (upregulation) of P311
3) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852399 Disease Relevance 0.38 Pain Relevance 0
Our previous microarray analysis revealed that P311 was highly upregulated in hypertrophic scar tissue [3].
Positive_regulation (upregulated) of P311 associated with keloid scars
4) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852399 Disease Relevance 1.24 Pain Relevance 0
We previously screened the differentially expressed genes of human hypertrophic scar tissue and identified P311 gene as upregulated.
Positive_regulation (upregulated) of P311 associated with keloid scars
5) Confidence 0.34 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2852399 Disease Relevance 0.52 Pain Relevance 0

General Comments

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