INT305015

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ASPN) proteinaceous extracellular matrix (ASPN)
Anatomy Link Frequency
margin 2
internal 2
ASPN (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 4 48.08 Quite Low
Inflammation 8 39.68 Quite Low
fibrosis 12 39.12 Quite Low
metalloproteinase 12 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dermal Scarring 192 100.00 Very High Very High Very High
Osteoarthritis 4 48.08 Quite Low
Disease 100 46.64 Quite Low
Necrosis 8 44.76 Quite Low
Cancer 24 44.40 Quite Low
Wound Healing 12 43.28 Quite Low
Apoptosis 12 41.76 Quite Low
INFLAMMATION 8 39.68 Quite Low
Fibrosis 4 39.12 Quite Low
Keloid Scars 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A statistically significant (P < .05) differential expression and a fold change of more than 2 were determined between keloid margin and internal control biopsy samples for 10 genes, including ACAN, ASPN, C5orf13, HIF1A, IGFBP7, INHBA, LGALS1, PTN, SERPINH1, and TNFAIP6 (Table 5).
Gene_expression (expression) of ASPN in internal associated with dermal scarring
1) Confidence 0.48 Published 2010 Journal Eplasty Section Body Doc Link PMC2851107 Disease Relevance 0.23 Pain Relevance 0
Ten of these 19 genes, including ACAN, ASPN, C5orf13, HIF1A, IGFBP7, INHBA, LGALS1, PTN, SERPINH1, and TNFAIP6 (Table 5), demonstrated a statistically significant difference for the gene expression levels between keloid margin and internal control skin.
Gene_expression (expression) of ASPN in internal associated with dermal scarring
2) Confidence 0.21 Published 2010 Journal Eplasty Section Body Doc Link PMC2851107 Disease Relevance 0.67 Pain Relevance 0
A statistically significant (P < .05) differential expression and a fold change of more than 2 were determined between keloid margin and internal control biopsy samples for 10 genes, including ACAN, ASPN, C5orf13, HIF1A, IGFBP7, INHBA, LGALS1, PTN, SERPINH1, and TNFAIP6 (Table 5).
Gene_expression (expression) of ASPN in margin associated with dermal scarring
3) Confidence 0.16 Published 2010 Journal Eplasty Section Body Doc Link PMC2851107 Disease Relevance 0.23 Pain Relevance 0
Ten of these 19 genes, including ACAN, ASPN, C5orf13, HIF1A, IGFBP7, INHBA, LGALS1, PTN, SERPINH1, and TNFAIP6 (Table 5), demonstrated a statistically significant difference for the gene expression levels between keloid margin and internal control skin.
Gene_expression (expression) of ASPN in margin associated with dermal scarring
4) Confidence 0.07 Published 2010 Journal Eplasty Section Body Doc Link PMC2851107 Disease Relevance 0.67 Pain Relevance 0

General Comments

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