INT305034

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.51
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Adcy8, Adcy1) plasma membrane (Adcy1) nucleus (Adcy1)
Adcy8 (Mus musculus)
Adcy1 (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 18 99.52 Very High Very High Very High
Pain 25 97.52 Very High Very High Very High
nMDA receptor 7 96.60 Very High Very High Very High
Central nervous system 3 95.72 Very High Very High Very High
Lasting pain 20 92.60 High High
Spinal cord 4 89.28 High High
Inflammation 9 87.80 High High
allodynia 10 67.84 Quite High
antagonist 3 65.00 Quite High
agonist 1 60.32 Quite High
Disease Link Frequency Relevance Heat
Pain 50 97.52 Very High Very High Very High
Targeted Disruption 39 96.48 Very High Very High Very High
INFLAMMATION 10 87.80 High High
Injury 14 87.12 High High
Nociception 6 82.16 Quite High
Nervous System Injury 6 77.36 Quite High
Neuropathic Pain 19 67.84 Quite High
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To examine the roles of AC1 and AC8 in behavioral sensitization within the ACC, an area mediating the emotional component of pain, we used AC1 and AC8 knockout mice as well as AC1&8 double knockout (DKO) mice to determine the roles of these ACs in chronic pain [7] (Fig. 1).
AC8 Spec (examine) Regulation (roles) of Localization (sensitization) of AC1 associated with targeted disruption, pain, lasting pain and anterior cingulate cortex
1) Confidence 0.35 Published 2010 Journal Current Genomics Section Body Doc Link PMC2851120 Disease Relevance 1.51 Pain Relevance 0.77

General Comments

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