INT305265

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos3) Golgi apparatus (Nos3) cytoplasm (Nos3)
signal transduction (Nos3) oxidoreductase activity (Nos3) nucleolus (Nos3)
Obsty1 (Mus musculus)
Nos3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 14.80 Low Low
cytokine 1 13.76 Low Low
ketamine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 169 100.00 Very High Very High Very High
Aging 124 100.00 Very High Very High Very High
Stress 17 90.40 High High
Myocardial Infarction 2 79.32 Quite High
INFLAMMATION 2 14.80 Low Low
Lifespan 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 5 5.00 Very Low Very Low Very Low
Insulin Resistance 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our hands, both
               obesity and aging independently decreased the phosphorylation of Akt and eNOS
               without any additive effects between the two, consistent with our data on
               mechanical, intracellular Ca2+ and
                   O2? 
obesity Negative_regulation (decreased) of Phosphorylation (phosphorylation) of eNOS associated with aging and obesity
1) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852499 Disease Relevance 0.78 Pain Relevance 0

General Comments

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