INT305271

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 4.86
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lep) extracellular space (Lep) extracellular region (Lep)
intracellular (Lep) lipid metabolic process (Lep)
Anatomy Link Frequency
Cardiomyocyte 2
Lep (Mus musculus)
Obsty1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
ketamine 5 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 845 100.00 Very High Very High Very High
Aging 620 100.00 Very High Very High Very High
Stress 85 99.80 Very High Very High Very High
Death 20 98.36 Very High Very High Very High
Metabolic Syndrome 15 93.84 High High
Apoptosis 5 91.64 High High
Coronary Heart Disease 15 79.64 Quite High
Hypertension 10 50.28 Quite High
Hyperlipidemia 5 48.96 Quite Low
Insulin Resistance 20 48.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Influence of age and ob/ob obesity on leptin receptor (Ob-R)
                   and STAT3 activation
leptin Binding (receptor) of obesity associated with obesity
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852499 Disease Relevance 0.92 Pain Relevance 0
Interaction between Age and Obesity on Cardiomyocyte Contractile
                   Function: Role of Leptin and Stress Signaling

Objectives

Leptin Binding (Interaction) of Obesity in Cardiomyocyte associated with stress and obesity
2) Confidence 0.06 Published 2010 Journal PLoS ONE Section Title Doc Link PMC2852499 Disease Relevance 0.80 Pain Relevance 0
Nevertheless, the
               interaction between obesity and aging on cardiac function, with a focus on leptin
               signaling, has not been elaborated. 
leptin Binding (interaction) of obesity associated with aging and obesity
3) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852499 Disease Relevance 1.17 Pain Relevance 0
Nevertheless, the
               interaction between obesity and aging on cardiac function, with a focus on leptin
               signaling, has not been elaborated. 
leptin Binding (interaction) of obesity associated with aging and obesity
4) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852499 Disease Relevance 1.17 Pain Relevance 0
Interaction between Age and Obesity on Cardiomyocyte Contractile
                   Function: Role of Leptin and Stress Signaling

Objectives

Leptin Binding (Interaction) of Obesity in Cardiomyocyte associated with stress and obesity
5) Confidence 0.06 Published 2010 Journal PLoS ONE Section Title Doc Link PMC2852499 Disease Relevance 0.80 Pain Relevance 0

General Comments

This test has worked.

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